Z. Naturforsch. 2014,
69b, 1021 – 1025
doi:10.5560/ZNB.2014-4114
The Structure Elucidation and Antimicrobial Activities of Nonsterol Triterpenoids from Ixeris chinensis
Qing-Hu
Wang,
Na-Ren-Chao-Ke-Tu
Han,
Na-Yin-Tai
Dai,
Xiao-Lan
Wu,
Wen-Quan
Tai,
Jie-Si
Wu, and
Rong-Jun
Wu
College of Traditional Mongolian Medicine, Inner Mongolia University for Nationalities, No. 536 Hulinhe District, Tongliao 028000, P. R. China
Reprint requests to Prof. Qing-Hu Wang. Fax: +86-0475-8314242. E-mail:
wqh196812@163.com
Received May 29, 2014 / published online October 12, 2014
An investigation of the petroleum ether extract from Ixeris chinensis Nakai has led to the isolation of a new compound, 3-O-acetyl-22,28-cyclobauer-7-en-3β-ol (1), together with four known compounds which have been isolated from this plant for the first time, namely taraxast-20-en-3β-ol (2), 3-O-acetyl-taraxast-20-en-3β-ol (3), taraxast-20(30)-en-3β-ol (4), and 3-O-acetyl-taraxast-20(30)-en-3β-ol (5). The structures of the isolated compounds have been elucidated on the basis of spectroscopic methods including UV, IR, ESI-MS, 1D NMR, 2D NMR techniques, and by comparison with data reported in the literature. All compounds have been evaluated for their activity against various bacteria and shown to give good results.
Key words: Ixeris chinensis Nakai, Nonsterol Triterpenoids, Antimicrobial Activity, 3-O-Acetyl-22,28-cyclobauer-7-en-3β-ol