Z. Naturforsch. 2013,
68b, 289 – 292
doi:10.5560/ZNB.2013-3014
A Polyketide Metabolite from an Endophytic Fusarium equiseti in a Medicinal Plant
Yoshihito
Shiono1,
Fumiaki
Shibuya1,
Tetsuya
Murayama1,
Takuya
Koseki1,
Herve Martial Poumale
Poumale2, and
Bonaventure Tchaleu
Ngadjui2
1 Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata 997-8555, Japan
2 Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, P. O. Box 812, Yaoundé, Cameroon
Received January 16, 2013 / published online March 20, 2013
A new polyketide, fusaequisin A (1), was isolated from rice cultures of Fusarium equiseti SF-3-17, an endophytic fungus previously discovered during screening of medicinal plants in Cameroon. The structure of 1 was determined using spectroscopic methods. Fusaequisin A (1) exhibited moderate antimicrobial activity against Staphylococcus aureus NBRC 13276 and Pseudomonas aeruginosa ATCC 15442 at a concentration of 200 μg per disk.
Key words: Endophyte, Fusarium equiseti, Antimicrobial Activity