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Z. Naturforsch. 2013,
68b, 182 – 186
doi:10.5560/ZNB.2013-2251
Regio- and Chemoselective Synthesis of 5-Aroyl-NH-1,3-oxazolidine-2-thiones
Department of Chemistry, Faculty of Sciences, University of Kurdistan, P. O. Box 66315-416, Sanandaj, I. R. Iran
Reprint requests to Dr. Farzad Nikpour. Fax: +98 (871) 662 4133 or +98 (871) 666 0075. E-mail:
fnikpour@uok.ac.ir or
farzad_nikpour@yahoo.com
Received September 3, 2012 / published online February 20, 2013
A one-pot synthesis of 5-aroyl-NH-1,3-oxazolidine-2-thiones by a regio- and chemoselective reaction of α-epoxyketones with thiourea or sodium thiocyanate in the presence of p-toluenesulfonic acid as catalyst in tetra-n-butylammonium chloride is described.
Key words: NH-Oxazolidine-2-thiones, Chemoselective Reaction, Regioselective Reactions, One-pot Synthesis, Ionic Liquid